The Bisphenol A Profile determines exposure to bisphenol A, triclosan, and 4-nonylphenol which are considered harmful endocrine disruptors and are found in many of the products we use every day.
The Bisphenol A Profile can help identify exposure to the common endocrine disruptors BPA, triclosan, and 4-nonylphenol. Exposure to endocrine disruptors may play a role in obesity, adult onset diabetes, hormonal and neurological development disorders, and thyroid disruption. Awareness of toxicity can assist in treatment planning to help achieve wellness. This easy-to-use profile consists of a simple urine collection.
Endocrine disruptors weakly bind to estrogen receptors which can affect the endocrine, nervous, and immune systems as well as block thyroid hormone action. Exposure to chemicals that are xenoestrogens disrupt the proper function of the body’s endocrine system. Children and babies in the womb are most susceptible to hormonal and neurological development issues from exposure.
Hamrful endocrine disruptors
Symptoms and conditions:
Adult onset diabetes
Chronic neurological illnesses
Increased risk of cancer
Neurological development disorders
Reproductive system disorders
Sources of exposure:
Bisphenol A (BPA) is found mostly in plastics labeled with the recycling codes 3 or 7. BPA is a key monomer used to produce polycarbonate plastic. This type of plastic is usually clear and shatter-proof. Other uses of BPA consist of epoxy resins, which are used to coat the inside of food and beverage cans. BPA studies have been linked to obesity, neurological development delays in infants, thyroid disruption, developmental issues of sexual organs in infants, and sexual dysfunction in adults. Exposure to BPA occurs mostly through digestion of food and liquids that have been stored and heated in plastic materials.
Triclosan is an anti-microbial and preservative agent used in personal care products such as toothpaste, shaving cream, and hand soaps. Exposure occurs from use of these products in the home. Triclosan bioaccumulates in the body and is considered to block thyroid activity affecting metabolism and thyroid hormone signaling.
Often used as a surfactant, 4-nonylphenol is found in industrial detergents, foaming agents, dispersants, and emulsifiers. Most exposure is through the skin. 4-Nonylphenol is also an endocrine disruptor.
Gas Chromatography/Mass Spectrometry